Postdoctoral researcher – Disease Modelling & Screening Platform (DMSP)

(Valid from 08/11/2023 to 31/01/2024)   

Language: English (UK) 

Location Belval 

Country: Luxembourg  

Organisation data: Luxembourg Centre for Systems Biomedicine (LCSB)

Job Number: UOL06084 

Contract Type: Fixed Term Contract 

Duration 24 Month 

Schedule Type: Full Time 

Work Hours 40.0 Hours per Week 

Expected Start Date: 01/01/2024   

Functions: Postdoctorant 

Job (internal): Postdoctoral researcher     

About us...

The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character. The University was founded in 2003 and counts more than 6,700 students and more than 2,000 employees from around the world. The University’s faculties and interdisciplinary centres focus on research in the areas of Computer Science and ICT Security, Materials Science, European and International Law, Finance and Financial Innovation, Education, Contemporary and Digital History. In addition, the University focuses on cross-disciplinary research in the areas of Data Modelling and Simulation as well as Health and Systems Biomedicine.

Within the University, the Luxembourg Centre for Systems Biomedicine (LCSB) is a highly interdisciplinary research centre (IC), integrating experimental biology, clinical research, and computational biology approaches to develop the foundation of a future predictive, preventive and personalized medicine.

The Disease Modelling & Screening Platform (DMSP) is a dynamic scientific service provider, dedicated to advancing translational research projects at the LCSB. DMSP operates under the joint auspices of the LCSB and the Luxembourg Institute of Health (LIH), with its cutting-edge laboratory infrastructure established at the LCSB site.

At DMSP, we are committed to advancing early drug discovery through the implementation of cell and organoid-based phenotypic screening. Our primary goal is to support research teams within the LCSB and LIH, as well as academic and commercial partners both in Luxembourg and abroad. Our overarching vision is to provide access to state-of-the-art infrastructure, complemented by expert guidance in experimental design, model selection, compound delivery, and the development and execution of high-content analysis.

  Your Role...

Area: early drug discovery by implementing cell and organoid-based phenotypic screening, automated HC/HT screening

• Design/perform various experiments using the portfolio of DMSP (assay development and optimization, compound library screening, identification of lead candidates).
• Data analysis, preparation and presentation of results in written reports and presentations, protocols, SOP’s and other documentation (LIMS).
• Maintain and troubleshoot analytical instruments as needed.
• Critically review the experimental design of projects which include core technologies.
• Interact and collaborate with scientists at all levels (PhD students, postdocs, principal investigators, professors).
• Participate in grant writing.
• Prepare and submit scientific material for peer review for publication independently or in collaboration with other researchers.

  What we expect from you…

• A Ph.D. in biology, chemistry, biochemistry, or a related field is required, demonstrating a strong foundation in relevant scientific disciplines.
• Possess extensive experience in the principles of drug discovery, miniaturization, and automation engineering, as well as proficiency in imaging and confocal microscopy techniques.
• A proven track record in translational research, including hands-on experience in assay development and high-content/high-throughput screening.
• Ability to effectively collaborate with cross-functional teams, including project partners from diverse technology areas such as biology, compound management, artificial intelligence, bioinformatics, and analytical chemistry.
• Willingness to contribute to the operational management and strategic development of our technology platform.
• Strong interpersonal and stakeholder management skills, capable of working both collaboratively as part of a team and independently.
• Familiarity with all aspects of high content screening, including the adaptation and scaling of established assays to the screening platform, 3D cell culture, and the use of organoids, is a significant advantage.
• Exceptional oral and written communication skills in English are essential, with the ability to effectively present technologies and research results in both internal meetings and conferences.

  Here’s what awaits you at the LCSB...

• Excellent work environment with state-of-the-art infrastructure, laboratory and administrative support
• Truly connected. We work together with hospitals and research institutes on a national and international level as well as industrial partners. Connection between science and society is very important to us. From our school lab – the Scienteens Lab – to the different outreach activities and collaborative partnerships with patient associations, we love to listen to society’s needs and share our passion for science
• Be part of a multicultural team. At the LCSB we have more than 50 nationalities. Throughout the year, we organise team-building events, networking activities and more

Find out more about us!

  In Short...

• Contract type: Fixed Term Contract 24 Month
• Work hours: Full Time 40.0 Hours per Week
• Location: Belval
• Job reference: UOL06084

The yearly gross salary for every Postdoctoral Researcher at the UL is EUR 83099 (full time)

  How to apply...

Applications should be submitted online and include:

• Curriculum Vitae
• Cover letter
• Any additional material highlighting experience in working with visual assays for high content screening (e.g., training certificates), as well as other relevant qualification

Early application is highly encouraged, as the applications will be processed upon reception. Please apply formally through the HR system. Applications by email will not be considered.

The University of Luxembourg embraces inclusion and diversity as key values. We are fully committed to removing any discriminatory barrier related to gender, and not only, in recruitment and career progression of our staff.

  In return you will get…

• Multilingual and international character. Modern institution with a personal atmosphere. Staff coming from 90 countries. Member of the “University of the Greater Region” (UniGR)
• A modern and dynamic university. High-quality equipment. Close ties to the business world and to the Luxembourg labour market. A unique urban site with excellent infrastructure
• A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and with numerous non-academic partners such as ministries, local governments, associations, NGOs …
• Find out more about the University
• Addresses, maps & routes to the various sites of the University

  About the University of Luxembourg... University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character. The University was founded in 2003 and has more than 6,700 students and more than 2,000 employees from around the world. The University’s faculties and interdisciplinary centres focus on research in the areas of Computer Science and ICT Security, Materials Science, European and International Law, Finance and Financial Innovation, Education, Contemporary and Digital History. In addition, the University focuses on cross-disciplinary research in the areas of Data Modelling and Simulation as well as Health and System Biomedicine. Times Higher Education ranks the University of Luxembourg #3 worldwide for its “international outlook,” #20 in the Young University Ranking 2021 and among the top 250 universities worldwide.