Post-doctoral Position Institute of NeuroPhysiopathology - Aix-Marseille Université - CNRS

RESEARCHER PROFILE: Postdoc / R2: PhD holders 

RESEARCH FIELD(S) AND DISCIPLINES1: Medical and Natural Sciences

JOB /OFFER DESCRIPTION 

The INP is looking for a Post-doctoral researcher wishing to conduct innovative research by joining the Nivet lab.

The Institute of NeuroPhysiopathology (INP) at Aix-Marseille Université/CNRS combines basic and translational research in a stimulating and friendly working environment (https://inp.univ-amu.fr). The Nivet lab is at the forefront of innovative discoveries, and we are seeking a highly motivated and talented Post-Doctoral Fellow Specialist in CRISPR-based Genome Editing to join our dynamic team. We are committed to making a positive impact on human health by conducting cutting-edge research. The candidate will work in the context of a collaborative effort to lead a research project carrying conceptual and technical novelty, being at the interface between fundamental and applied research. 

As a Post-Doctoral Fellow Specialist in CRISPR-based Genome Editing, you will be an integral part of our research team. You will have the opportunity to work on groundbreaking projects aimed at applying CRISPR-based genome editing techniques to generate cell models able to address new biological questions with translational perspectives. Your responsibilities will include, but are not limited to:

• Designing and executing experiments related to CRISPR-based genome editing in various model systems (in vitro principally). 
• Developing and optimizing CRISPR-based protocols and techniques. 
• Designing and executing drug treatments on various cellular models.
• Performing DNA/RNA isolation, PCR, qPCR, cloning, and other molecular biology assays.
• Collaborating with interdisciplinary teams and a private partner to advance research goals.
• Writing regular data reports. 
• Contributing to the publication of research findings in peer-reviewed journals.
• Mentoring and training junior team members.

The INP is located on the Marseille Health Sciences campus, alongside other leading laboratories covering a wide range of topics. In addition, the INP offers an internationally competitive research environment in partnership with the biotechnology spin-off company Vect-Horus. State-of-the-art technology facilities include super-resolution and HCS microscopy, an iPS cell platform, a biophysics platform for the study of molecular interactions, and a SPF rodent facility with space for surgery and animal behaviour studies. Other facilities available on campus include a virus production and use facility, MRI and PET imaging.

The INP is a member of NeuroMarseille (https://neuro-marseille.org), the 2nd largest neuroscience community in France, and of NeuroSchool, the Graduate School of Neuroscience (https://neuro-marseille.org/en/training/). The INP is also part of the CIVIS European University (https://civis.eu/fr), thus favouring scientific and training synergies in an international environment.

Last but not least, the INP is located in the center of Marseille, close to the Parc National des Calanques and the scenic and cultural charms of Provence, which perfectly complements the dynamism of Marseille and its region as a place to live and work in science.

WHAT WE OFFER: 

• A one-year contract that will be renewable.
• Competitive salary commensurate with research experience.
• Comprehensive benefits package, including health, dental, and retirement plans.
• Access to state-of-the-art research facilities and resources.
• Collaborative and innovative work environment
• AMU supports diversity and equal opportunities. Women and persons with disability are encouraged to apply and are assured of equal opportunity in the multi-stage selection process that will comply with French employment laws, AMU's commitment to the HRS4R, Euraxess good practice guidelines, and A*Midex requirements for excellence. Candidates will be informed at each stage of the selection process, which will require a minimum of one interview (on site or via an e-meeting).
• The Euraxess Center of Aix-Marseille Université informs foreign visiting professors, researchers, postdoc and PhD candidates about the administrative steps to be undertaken prior to arrival at AMU and the various practical formalities to be completed once in France: visas and entry requirements, insurance, help finding accommodation, support in opening a bank account, etc. More information on AMU EURAXESS Portal 

TYPE OF CONTRACT: TEMPORARY / JOB STATUS: FULL TIME /HOURS PER WEEK: 35

JOB NOT FUNDED THROUGH AN EU RESEARCH FRAMEWORK PROGRAMME               

APPLICATION DEADLINE: 31th January 2024

ENVISAGED STARTING DATE:  between February 2024 and March 2024

ENVISAGED DURATION: 1 year (renewable)

WORK LOCATION(S): The Institute of Neuro Physiopathology (INP), Campus Timone, Faculté de Médecine, 13005 Marseille, France

QUALIFICATIONS, REQUIRED EDUCATION LEVEL, PROFESSIONAL SKILLS, RESEARCH REQUIREMENTS Candidates must meet the following criteria:

• Ph.D. in Molecular Biology, Biochemistry, Cell Biology, Genetics, or a related field.
• A previous post-doctoral experience would be a plus.
• Strong background in CRISPR-based genome editing techniques. Experience and autonomy with genome editing (KO, Ki), including CRISPRa and CRISPRi systems, is mandatory.
• Hands-on experience with molecular biology techniques, cell culture, gene expression analysis.
• Proficiency in data analysis tools and software.
• An interest in drug screening assays and a first-hand experience with High content screening/analysis would be considered as a strong plus.
• Excellent written and oral communication skills (minimum English language proficiency requirements: C1 advanced). 
• An excellent early-career publication record.
• Ability to work independently and as part of a collaborative team.

SOFT SKILLS: Autonomy, Teamwork, Analytical and critical thinking, Listening and observing, Empathy, Flexibility and adaptability, Linguistics, communicative, Co-operation, Conflict-resolution

REQUESTED DOCUMENTS OF APPLICATION, SELECTION PROCESS: 

• A complete CV and list of publications.

• A cover letter describing past and current scientific activities/achievements (2 pages max).

• Two references for letters of recommendation.

WHERE TO APPLY: emmanuel.nivet@univ-amu.fr

Applications must be sent in a single PDF file to Dr. Emmanuel Nivet: emmanuel.nivet@univ-amu.fr