PhD student position in computational systems biology

(Valid from 18/10/2023 to 29/02/2024)   

Language: English (UK) 

Country: Luxembourg   

Organisation data: Department of Life Sciences and Medicine (DLSM) 

Job Number: UOL06020 

Contract Type: Fixed Term Contract 

Duration 36 Month 

Schedule Type: Full Time 

Work Hours 40.0 Hours per Week 

Expected Start Date: 01/03/2024   

Functions: PhD Candidates 

Job (internal): Doctoral researcher-Marie Curie     

The University | About us...

The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character. The University was founded in 2003 and counts more than 6,700 students and more than 2,000 employees from around the world. The University’s faculties and interdisciplinary centres focus on research in the areas of Computer Science and ICT Security, Materials Science, European and International Law, Finance and Financial Innovation, Education, Contemporary and Digital History. In addition, the University focuses on cross-disciplinary research in the areas of Data Modelling and Simulation as well as Health and System Biomedicine. Times Higher Education ranks the University of Luxembourg #3 worldwide for its “international outlook,” #20 in the Young University Ranking 2021 and among the top 250 universities worldwide.

The Faculty of Science, Technology and Medicine (FSTM) contributes multidisciplinary expertise in the fields of Mathematics, Physics, Engineering, Computer Science, Life Sciences and Medicine. Through its dual mission of teaching and research, the FSTM seeks to generate and disseminate knowledge and train new generations of responsible citizens, in order to better understand, explain and advance society and environment we live in.

PhD student position in computational systems biology / Topic: Spatial modelling of cancer metabolic networks on multi-cell population level

Your Role...

Project Objectives: Methodological advances enable a deeper characterization of tumour tissues on the cellular (single-cell omics) and spatial level (imaging). Computational methods are needed for data integration and for gaining deeper insights, e.g., into tumour metabolic rewiring. In this DC we aim to: 1. Develop a novel computational approach for the integration of single-cell RNA-Seq and imaging data towards the detailed metabolic network modelling of cancer tissue on a multi-cell population level. 2. Together with consortium partners, apply this framework for the deeper characterization of metabolic alterations in TNBC and for the prediction of novel drug candidates and combinations. 

Secondment(s): The applicant will undertake two secondments including secondment 1 at Galway University with Professor Glynn (approx. 3 months) and secondment 2 at University of Siena with Professor Morbidelli (approx. 3 months). 

 What we expect from you…

Required applicant profile: MSc in Systems Biology, Computational Biology, Bioinformatics or equivalent

Desired Skills: Strong background in computational and molecular biology, especially data, network and image analysis, as well as in biochemistry

In Short...

• Contract Type: Fixed-term contract 36 months (extendable up to 48 months if required)
• Work Hours: Full time 40 hours / week
• Employee and student status
• Gross salary: 37 022.04 € gross per annum plus mobility and family allowances as applicable and in line with the EC rules for Marie Sklodowska Curie Doctoral Networks 2022
• Job Reference: UOL06020

How to apply...

Applications should include:

• Curriculum Vitae
• Cover letter

Early application is highly encouraged, as the applications will be processed upon reception. Please apply ONLINE formally through the HR system. Applications by email will not be considered.

The University of Luxembourg embraces inclusion and diversity as key values. We are fully committed to removing any discriminatory barrier related to gender, and not only, in recruitment and career progression of our staff.

In return you will get…

• Multilingual and international character. Modern institution with a personal atmosphere. Staff coming from 90 countries. Member of the “University of the Greater Region” (UniGR).
• A modern and dynamic university. High-quality equipment. Close ties to the business world and to the Luxembourg labour market. A unique urban site with excellent infrastructure.
• A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and with numerous non-academic partners such as ministries, local governments, associations, NGOs …
• Find out more about the University
• Addresses, maps & routes to the various sites of the University

Further information...

For more information, contact: Professor Thomas Sauter / thomas.sauter@uni.lu

Lab Website: https://scholar.google.de/citations?user=6TU6vO8AAAAJ